Figure 4.
Regulation of the PI3K/AKT pathway in ARPE19 cells by CTGF. (A) Representative western blot analysis of p-PI3K/PI3K and p-Akt/Akt in ARPE19 cells treated with CTGF (15, 30 and 60 ng/ml). (B) Quantification of p-PI3K/PI3K levels; n=3. *P<0.05, ***P<0.001 vs. control group. CTGF, connective tissue growth factor; p-, phosphorylated.