Table 4. Associations Between Maternal Socioeconomic Measures and Brain Lobe Volumes and Cortical Featuresa.
Lobe volume, cm3 | LGI × 10−3 | Sulcal depth × 10−3 mm | ||||
---|---|---|---|---|---|---|
β (95% CI) | P value | β (95% CI) | P value | β (95% CI) | P value | |
Education level | ||||||
Frontal lobe | 0.91 (0.22 to 1.59) | .01b | −13 (−23 to −3) | .01b | −25 (−64 to 15) | .22 |
Parietal lobe | 0.90 (0.43 to 1.37) | <.001b | −29 (−45 to −14) | <.001b | −116 (−171 to −62) | <.001b |
Temporal lobe | 0.54 (0.27 to 0.82) | <.001b | −18 (−30 to −6) | .005b | −62 (−105 to −18) | .01b |
Occipital lobe | 0.23 (0.02 to 0.45) | .03b | −28 (−42 to −15) | <.001b | −94 (−136 to −53) | <.001b |
Occupation level | ||||||
Frontal lobe | 0.67 (0.16 to 1.17) | .01b | −10 (−17 to −3) | .01b | −22 (−52 to 7) | .13 |
Parietal lobe | 0.62 (0.27 to 0.97) | .001b | −22 (−33 to −10) | <.001b | −85 (−125 to −44) | <.001b |
Temporal lobe | 0.38 (0.17 to 0.59) | <.001b | −13 (−22 to −4) | .005b | −48 (−81 to −16) | .003b |
Occipital lobe | 0.17 (0.01 to 0.33) | .04b | −18 (−28 to −8) | .001b | −64 (−95 to −33) | <.001b |
SES score | ||||||
Frontal lobe | 0.07 (0.02 to 0.13) | .01b | −1.1 (−1.9 to −0.3) | .01b | −2.4 (−5.5 to 0.7) | .14 |
Parietal lobe | 0.07 (0.03 to 0.11) | <.001b | −2.4 (−3.6 to −1.2) | <.001b | −9.5 (−13.8 to −5.3) | <.001b |
Temporal lobe | 0.04 (0.02 to 0.07) | <.001b | −1.5 (−2.4 to −0.5) | .003b | −5.3 (−8.7 to −1.9) | .002b |
Occipital lobe | 0.02 (0.002 to 0.04) | .03b | −2.1 (−3.2 to −1.0) | <.001b | −7.3 (−10.6 to −4.1) | <.001b |
Abbreviations: GA, gestational age; LGI, local gyrification index; SES, socioeconomic status.
Adjusted for GA at magnetic resonance imaging scan (wk) and fetal sex (ie, female: 0; male: 1).
q < 0.05.