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Uptake of α-synuclein constructs by live SH-SY5Y cells. Top row: representative low-magnification images of SH-SY5Y cells merging confocal fluorescence and DIC channels are shown. Cells were fixed after 2-h continuous exposure to Cy-5-labeled αS-1, αS-2, and αS-4. Bottom row: representative higher-resolution images showing punctate (squares) and diffuse (circles) distributions of fluorescence from αS-1, αS-2, and αS-4 are shown. To see this figure in color, go online.
