. 2020 Jun 8;63(13):6834–6846. doi: 10.1021/acs.jmedchem.0c00208

Table 2. 2D East (Green) and West Library (Red) with TNKS2 IC₅₀ (nM), HEK293 IC₅₀ (nM), and Solubility (μM) Values Depicted^a.

graphic file with name jm0c00208_0009.jpg

# indicates that the compound was evaluated in a mouse pharmacokinetics analysis.

Table 2. 2D East (Green) and West Library (Red) with TNKS2 IC50 (nM), HEK293 IC50 (nM), and Solubility (μM) Values Depicteda.