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. 2021 Feb 17;108(3):431–445. doi: 10.1016/j.ajhg.2021.02.001

Figure 5.

Figure 5

Comparison of proportion of variance explained (PVE) per locus in African Americans and Europeans at known loci (n = 215 SNPs) via effects estimated on the lnOR and liability scales

(A) PVE is computed as 2p.q.ln(OR)2.

(B) PVE is computed as 2.p.alpha12 + 2.q.alpha22, where alpha1 and alpha2 are liability scale estimates.