Fig. 6.

Antimicrobial Resistance. a Presence (red) or absence (white) of resistance genes grouped by isolates within Panaroo clusters along the y-axis. Genes are named along the x-axis with mutational resistance represented by gene names highlighted by 2 asterisks and grouped by AMR class. AG, aminoglycosides; LZ, linezolid; FI, folate inhibitors; FQ, fluoroquinolones; MLS, macrolide-lincosamide-streptogramin; DAP, daptomycin; TET, tetracycline; VAN, vancomycin; and CAT, chloramphenicol. b Heatmap of the average number of antimicrobial resistance genes resulting in resistance within isolates by country. No isolates were included from grey shades countries. c Circular dendrogram of the tetM gene with designated cluster by colour depicted in the outer ring. Evidence of clustering is still seen (e.g. clusters 7, 8 and 9) but extensive transfer of alleles between clusters by horizontal gene transfer is evident