Table II.
Antimicrobial resistance profiles of the studied K. pneumoniae isolates.
| Patient ID/Isolate no. | 3 | 6965 | 6976/1 | 6976/2 | 1 | 6968 | 2 | 4 | 154/25428 | 7/25804 | 11/25808 | 13/25810 | 6 | 7 | 5 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Antibiotics: | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | MIC (pg/ml) | R/I/S | |
| Penicillins | Amoxicillin/Clavulanic acid | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R |
| Ampicillin | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | |
| Cephalosporins | Cefaclor | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R |
| Cefuroxime | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | |
| Cefotaxime | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | |
| Cefotaxime/Cefotaxime + clavulanic acid | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | >16/>1 | R | |
| Ceftazidime | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | |
| Ceftazidime/Ceftazidime + clavulanic acid | >34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | 34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | >34/>4 | R | |
| Cefepime | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | |
| Carbapenems | Doripenem | >32 | R | 16 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R |
| Ertapenem | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | |
| Imipenem | >32 | R | >32 | R | 16 | R | 16 | R | >32 | R | >32 | R | >32 | R | >32 | R | >12 | R | 4 | S | 4 | S | 8 | I | >32 | R | >32 | R | >32 | R | |
| Meropenem | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | |
| Quinolone | Ciprofloxacin | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R |
| Aminoglycosides | Amikacin | 4 | S | 8 | S | 32 | R | 32 | R | 8 | S | 12 | R | 6 | S | 4 | S | 8 | S | 8 | S | 8 | S | 8 | S | 12 | R | 6 | S | 6 | S |
| Gentamycin | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | |
| Netylmycin | 128 | R | 4 | I | 64 | R | 64 | R | 128 | R | 32 | R | 16 | R | 16 | R | 12 | R | 16 | R | 16 | R | 16 | R | 32 | R | 16 | R | 16 | R | |
| Tobramycin | 64 | R | 64 | R | 32 | R | 32 | R | 64 | R | 64 | R | 64 | R | 64 | R | 32 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | 64 | R | |
| Other | Aztreonam | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R |
| Colistin | 0.50 | S | 0.75 | S | 0.125 | S | 0.125 | S | 0.50 | S | 0.50 | S | 0.50 | S | 0.50 | S | 0.50 | S | 0.50 | S | 0.75 | S | 0.50 | S | 0.50 | S | 0.50 | S | 0.50 | S | |
| Tetracycline | 32 | R | 128 | R | 8 | R | 8 | R | 32 | R | 32 | R | 32 | R | 8 | R | >256 | R | >256 | R | >256 | R | >256 | R | 8 | R | 8 | R | 128 | R | |
| Tigecycline | 2 | R | 8 | R | 4 | R | 4 | R | 2 | R | 2 | R | 2 | R | 4 | R | 0.75 | R | 0.75 | R | 1.0 | R | 2 | R | 4 | R | 4 | R | 8 | R | |
| Trimethoprim/Sulfamethoxazole | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | >32 | R | |
| Fosfomycin | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | >256 | R | R>256 | R | >256 | R | >256 | R | >256 | R | >256 | R | |
MIC – Minimum Inhibitory Concentration; R – Resistant; I – Susceptible, increased exposure; S – Susceptible