Figure 3.

Anti–SARS-CoV-2 antibody in samples from pregnant and nonpregnant women

Peripheral serum or plasma was used to titer IgG antibodies against SARS-CoV-2 full-length spike (S), S receptor-binding domain, and whole virus nAbs. A, Anti-S IgG; B, anti–S-RBD IgG; and C, nAb AUC titrations in serum or plasma from pregnant (P) (n=17) and nonpregnant (NP) (n=17) women. The dashed line denotes the median AUC for SARS-CoV-2–negative samples. Above each boxplot is the proportion of samples with detectable antibody; the single asterisk represents P<.05 using the Kruskal-Wallis, Dunn multiple comparisons, Wilcoxon exact, or chi-square tests.

AUC, area under curve; IgG, immunoglobulin G; nAb, neutralizing antibody; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Sherer et al. Coronavirus disease 2019 and pregnancy. Am J Obstet Gynecol 2021.