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. 2021 Mar 30;225(3):301.e1–301.e14. doi: 10.1016/j.ajog.2021.03.028

Figure 4.

Figure 4

Association between antispike-RBD IgG and nAb in pregnant and nonpregnant women

A, Comparison between anti–S-RBD IgG and nAb AUC in pregnant women, with additional comparison of anti–S-RBD IgG and nAb responses between pregnant with (nAb titer ≥1:20) and without (nAb titers <1:20) detectable nAb. B, Comparison between anti–S-RBD IgG and nAb AUC in nonpregnant women. C and D, Anti–S-RBD IgG AUC and nAb analyzed as a function of detectability of nAb and days between PRC tests positive for SARS-CoV-2 and blood sample. E and F, Anti–S-RBD IgG AUC and nAb analyzed as a function of detectability of nAb and days since symptom onset and blood collection; there are missing data points because of unknown symptom onset date (n=4). Single asterisk represents P<.05 using the Wilcoxon exact test.

AUC, area under curve; IgG, immunoglobulin G; nAb, neutralizing antibody; RBD, receptor-binding domain; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Sherer et al. Coronavirus disease 2019 and pregnancy. Am J Obstet Gynecol 2021.