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. Author manuscript; available in PMC: 2021 Mar 30.
Published in final edited form as: Nat Catal. 2019 Oct 28;2(12):1071–1077. doi: 10.1038/s41929-019-0370-z

Fig. 1. Methods for the synthesis of deuterated aldehydes.

Fig. 1

a, Indirect approaches involving transformations of different functional groups to deuterated aldehydes. b, Direct approach employing transition metal catalyzed hydrogen-deuterium exchange of aromatic formyl groups. c, The current work using organocatalytic direct hydrogen-deuterium exchange of the aromatic, aliphatic and α, β-unsaturated formyl group.