Figure S13. Initial characterizations of the genome-wide analysis.
(A) Principal component analysis of RNASeq data performed in Partek Genomics Suite. (B) Gene ontology cellular component analysis performed in DAVID as described in the Materials and Methods section. Gene ontology Terms with greater than a −LOG10(P-value) of five are shown. (C) Fold changes and adjusted P-values for LOX mRNA in the differentially expressed genes of aortas from 2-mo Hutchinson–Gilford Progeria Syndrome and 2- and 24-mo WT mice.