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. 2021 Apr;18(4):632–640. doi: 10.1513/AnnalsATS.202007-805OC

Table 2.

Clinical symptoms and vital signs on admission

Clinical Symptoms and Vitals on Admission COVID-19 (n = 65) Influenza (n = 74) P Value*
Symptom duration before admission, median (IQR), d 7 (5–13) 3.5 (2–7) <0.001
Known sick contact, n/total n (%) 32/55 (58.2) 19/48 (39.6) 0.06
Symptoms on presentation, n (%)      
 Cough 53 (81.5) 50 (67.6) 0.06
 Sputum production 18 (27.7) 25 (33.8) 0.44
 Shortness of breath 54 (83.1) 51 (68.9) 0.05
 Sore throat 10 (15.4) 5 (6.8) 0.10
 Nasal congestion 7 (10.8) 11 (14.9) 0.47
 Rhinorrhea 9 (13.9) 9 (12.2) 0.77
 Subjective fever 41 (63.1) 30 (40.5) 0.008
 Chills 22 (33.9) 16 (21.6) 0.11
 Headache 13 (20.0) 9 (12.2) 0.21
 Myalgias 21 (32.3) 15 (20.3) 0.11
 Fatigue 23 (35.4) 35 (47.3) 0.16
Vital signs on ICU admission, n/total n (%)
 Fever, temperature >100.4°F or 38°C, n/total n (%) 28/64 (43.8) 27/68 (39.7) 0.64
 Heart rate >100 beats/min 21/65 (32.3) 46/72 (63.9) <0.001
 Respiratory rate ≥20 breaths/min 49/65 (75.4) 57/72 (79.2) 0.60
SOFA score on ICU admission, median (IQR)§ 6 (3–11) 6.5 (3–10) 0.62

Definition of abbreviations: COVID-19 = coronavirus disease; ICU = intensive care unit; IQR = interquartile range; SOFA = sequential organ failure assessment.

The total number is given if values are missing.

*

P values were calculated using a t test for continuous variables and a chi-square test or Fisher exact test for binary and categorical variables.

Not reported in 11 patients.

Symptoms were assumed to be absent if not reported.

§

Highest SOFA score within 24 hours of ICU admission.