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Pharmacokinetic and drug-likeness properties
| Compound | Violation of LoF | GI absorption | TPSA | BBB permeation | Veber’s rule violation | Synthetic accessibility |
|---|---|---|---|---|---|---|
| A1 | 0 | High | 128.84 | No | 0 | 5.63 |
| A2 | 0 | High | 90.90 | No | 0 | 4.24 |
| A3 | 0 | High | 100.13 | No | 0 | 4.43 |
| A4 | 0 | High | 111.13 | No | 0 | 3.14 |
| A5 | 0 | High | 96.22 | No | 0 | 4.77 |
