Table 1.

Number of genes targeted by fisetin (FIS) in lipopolysaccharide (LPS)-treated RAW264.7 cells

Genes up-regulated by LPS and down-regulated by fisetin			Genes down-regulated by LPS and up-regulated by fisetin
Fold change in LPS versus Con	Fold change in FIS+ LPS versus LPS	Number of genes	Fold change in LPS versus Con	Fold change in FIS+ LPS versus LPS	Number of genes
≥8	0.25< ~ ≤0.5	27	0.25< ~ ≤0.5	≥8	1
	0.125< ~ ≤0.25	21		4≤ ~ <8	55
	≤0.125	30		2≤ ~ <4	460
4≤ ~ <8	0.25 ~ ≤0.5	46	0.125< ~ ≤0.25	≥8	2
	0.125< ~ ≤0.25	32		4≤ ~ <8	42
	≤0.125	11		2≤ ~ <4	147
2≤ ~ <4	0.25< ~ ≤0.5	164	≤0.125	≥8	0
	0.125< ~ ≤0.25	27		4≤ ~ <8	2
	≤0.125	1		2≤ ~ <4	3