Table 3.

Univariate analysis of variables affecting the overall survival in the very elderly patients with colorectal cancer (n = 101)

Variable	No. of patients	Overall survival
		HR (95% CI)	p value
Male	53	0.908 (0.583–1.415)	0.670
BMI > 25 kg/m2	22	0.523 (0.290–0.942)	0.031a
PS 0–1	62	0.207 (0.126–0.339)	0.000a
Location: proximal	30	1.145 (0.708–1.850)	0.581
Stage: localized	68	0.186 (0.113–0.309)	0.000a
WD/MD	91	0.285 (0.144–0.567)	0.000a
DM	29	0.701 (0.426–1.154)	0.701
SIRT1 high	65	1.699 (1.057–2.733)	0.029a
SIRT2 high	58	0.534 (0.338–0.841)	0.007a

HR, hazard ratio; CI, confidence interval; BMI, body mass index; PS, performance status; WD, well-differentiated; MD, moderately differentiated; PD, poorly differentiated; DM, diabetes mellitus; SIRT1, sirtuin 1; SIRT2, sirtuin 2.

^ap < 0.05.