Figure 3. Diagnostic tests for cardiac amyloidosis.

(A) Electrocardiogram showing characteristic low voltages relative to left ventricle wall thickness, with a pseudo-infarct pattern with Q waves in the early precordial leads mimicking a prior anteroseptal myocardial infarction. (B and C) Transthoracic echocardiogram, parasternal long-axis and short-axis view, showing increased ventricular wall thickness and thickening of the mitral valve. (D and E) Longitudinal strain imaging using two-dimensional speckle tracking echocardiography reveals the characteristic bull’s-eye pattern of apical sparing. (F) ^99mTechnetium pyrophosphate scan shows grade 3 myocardial radiotracer uptake characteristic of transthyretin cardiac amyloidosis.