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Schematic presentation of a) fabrication of bFGF@PLGA microspheres; b) preparation of bFGF@PLGA/CHA/hydrogels through formation of dynamic imine/hydrazone bonds between aminated gelatin (NGel), adipic acid dihydrazide (ADH) and oxidized dextran (ODex), and further encapsulation of bFGF@PLGA microspheres and drug chlorhexidine acetate (CHA), leading to sequential release of CHA during wound healing.11 Copyright 2019 Elsevier.
