Table 4.
Qol. | Without PCT | n | With PCT | PCT effect β (95% CI) | ||||||
---|---|---|---|---|---|---|---|---|---|---|
EORT C QLQ C15 PAL | ||||||||||
Physical functioning* | ||||||||||
Baseline QoL | 83 | 41.8 | 17 | 34.9 | 10.96 (−0.12 to 22.89) | |||||
14 days QoL Emotional functioning* |
83 | 37.2 | 17 | 37.3 | ||||||
Baseline QoL | 86 | 72.7 | 17 | 69.1 | 10.56 (0.02 to 20.55) | |||||
14 days QoL | ||||||||||
Fatigue* | 86 | 74.8 | 17 | 83.3 | ||||||
Baseline QoL | 83 | 60.9 | 19 | 83.0 | −7.01 (−18.97 to 4.91) | |||||
14 days QoL | ||||||||||
Nausea and vomiting* | 83 | 57.4 | 19 | 65.5 | ||||||
Baseline QoL | 85 | 25.7 | 19 | 48.2 | −1.08 (−15.93 to 14.26) | |||||
14 days QoL | 85 | 15.8 | 19 | 17.5 | ||||||
Pain* | ||||||||||
Baseline QoL | 87 | 45.2 | 19 | 68.4 | −17.56 (−30.57 to −4.58) | |||||
14 days QoL | ||||||||||
Dyspnea* | 87 | 34.1 | 19 | 30.7 | ||||||
Baseline QoL | 87 | 33.3 | 18 | 38.9 | 4.82 (−8.24 to 21.20) | |||||
14 days QoL | 87 | 26.8 | 18 | 35.2 | ||||||
Insomnia* | ||||||||||
Baseline QoL | 87 | 40.6 | 18 | 42.6 | −9.40 (−24.57 to 5.99) | |||||
14 days QoL | ||||||||||
Appetite loss* | 87 | 31.4 | 18 | 22.2 | ||||||
Baseline QoL | 86 | 48.8 | 18 | 62.9 | −23.30 (−43.90 to −4.68) | |||||
14 days QoL | ||||||||||
Constipation* | 86 | 44.2 | 18 | 29.6 | ||||||
Baseline QoL | 85 | 25.8 | 18 | 57.4 | 6.78 (−15.18 to 26.87) | |||||
14 days QoL | 85 | 18.8 | 18 | 38.9 | ||||||
Global health status* | ||||||||||
Baseline QoL | 85 | 51.7 | 16 | 30.2 | 12.05 (−2.59 to 25.98) | |||||
14 days QoL | 85 | 58.0 | 16 | 60.4 | ||||||
EQ-5D | ||||||||||
EQ-5D** | ||||||||||
Baseline QoL | 79 | 0.55 | 18 | 0.44 | 0.10 (−0.12 to 0.29) | |||||
14 days QoL | 79 | 0.54 | 18 | 0.52 | ||||||
Palliative Outcome Scale (POS) | ||||||||||
POS total** | ||||||||||
Baseline QoL | 77 | 11.80 | 16 | 14.62 | −2.21 (−5.21 to 0.51) | |||||
14 days QoL | ||||||||||
POS physical** | 77 | 10.92 | 16 | 10.56 | ||||||
Baseline QoL | 85 | 3.09 | 18 | 4.28 | −0.15 (−1.04 to 0.83) | |||||
14 days QoL | ||||||||||
POS psychological** | 85 | 2.36 | 18 | 2.83 | ||||||
Baseline QoL | 84 | 6.69 | 18 | 8.22 | −0.83 (−2.25 to 0.58) | |||||
14 days QoL | 84 | 5.99 | 18 | 6.10 | ||||||
POS information** | ||||||||||
Baseline QoL | 82 | 1.87 | 18 | 2.39 | −0.68 (−1.98 to 0.71) | |||||
14 days QoL | 82 | 2.32 | 18 | 2.11 |
Adjusted for baseline score, age, sex, life expectancy, treatment status, WHO performance status, and type of admission. For all analysis, the group of patients without PCT consultation is the reference group.
EORTC QLQ C15 PAL: range 0–100. For physical functioning, emotional functioning, and global health status higher score implies better status. For individual symptoms, higher score implies a severe burden of symptoms (worse status).
EQ-5D: range −0.33 to −1; a higher score implies better QoL.