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. 2021 Mar 26;13:2835–2848. doi: 10.2147/CMAR.S294584

Table 3.

MMTV-Like env Sequence and Its Association with Clinicopathological Features in Breast Cancer Patients

Non-Familial Familial
N= 50 (%) N=30 (%)
MMTV MMTV
Positive Negative Positive Negative
N=38(76) N=12(24) N=21(70) N=9(30)
Age (years)
 <45 12 (75) 4(25) 11(78.6) 3(21.4)
 45 26(76.5) 8(23.5) 10(62.5) 6(37.5)
p-value 0.91 0.44
ER Status
 Positive 31 (73.8) 11(26.2) 14(73.7) 5(26.3)
 Negative 7 (87.5) 1 (12.5) 7(63.6) 4(36.4)
p-value 0.406 0.563
PR Status
 Positive 29 (78.4) 8(21.6) 13(65) 7(35)
 Negative 9 (69.2) 4 (30.8) 8(80) 2(20)
p-value 0.506 0.398
Tumor Size
 <5cm 14 (60.9) 9 (39.1) 12 (66.7) 6 (33.3)
 ≥5cm 24 (88.9) 3 (11.1) 9(75) 3 (25)
p-value 0.012 0.626
Lymph Node
 Positive 30 (78.9) 8(21.1) 17 (70.8) 7(29.2)
 Negative 8 (66.7) 4(33.3) 4(66.7) 2(33.3)
p-value 0.385 1.000
Tumor Grade
 G I, II 33(73.3) 12(26.7) 19(70.4) 8(29.6)
 G III 5(100) 0.0(0) 2(66.7) 1(33.3)
p-value 0.319 1.000
Safety Margin
 Positive 4(100) 0 (0.0) 2(66.7) 1(33.3)
 Negative 34(73.9) 21(26.1) 19(70.4) 8(29.6)
p-value 0.56 1.000
Pathological Type
 Invasive duct carcinoma 35 (76.1) 11(23.9) 17(65.4) 9(34.6)
 Invasive lobular carcinoma 3(75) 1 (25) 4 (100) 0(0.0)
p-value 1.000 0.287
Menopausal Status
 Premenopausal 15(71.4) 6(28.6) 14(70) 6(30)
 Postmenopausal 23(79.3) 6(20.7) 7(70) 3(30)
p-value 0.52 1.000
Laterality
 Right 24(77.4) 7(22.8) 12(80) 3(20)
 Left 13(72.2) 5(27.8) 9(60) 6(40)
p-value 0.683 0.427
Stage
 II 18(72) 7(28) 13(68.4) 6(31.6)
 III+IV 20(80) 5(20) 8(72.7) 3(27.3)
p-value 0.508 0.804
Hormonal Therapy
 Yes 8(88.9) 1(11.1) 5(50) 5(50)
 No 30 (73.2) 11(26.8) 16(80) 4(20)
p-value 0.317 0.091