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. 2021 Mar 30;16(3):e0236216. doi: 10.1371/journal.pone.0236216

Table 4. Lung injury scoring criteria.

Lung injury Score
Scale 0 1 2 3 4
Extent of lung injury Absence <25% 26 to 50% 51 to 75% >75%
Alveolar wall thickness ≤ 1 rbc > 1 ≤ 2 rbc 3 to 5 rbc 6 to 10 rbc > 10 rbc
Hyaline membranes Absence Presence NA NA NA
Neutrophilic alveolitis Absence <10 neutrophils/HPF 10 to 20/HPF 21 to 50/HPF > 50/HPF
Suppuration Absence Presence NA NA NA
Bronchial epithelial degeneration Absence Presence NA NA NA
Neutrophilic peribronchitis Absence <10 neutrophils/HPF 10 to 20/HPF 21 to 50/HPF > 50/HPF
Lympho-hiostiocytic peribronchitis Absence <10 mononuclear cells/HPF 10 to 20/HPF 21 to 50/HPF > 50/HPF
Vasculitis (inflammation) Absence Presence NA NA NA
Vasculitis (necrosis) Absence Presence NA NA NA
Emphysema Absence < 25% 25 to 50% to 75% > 75%
Hemorrhage Absence Presence NA NA NA

rbc: Red blood cells; NA: Not applicable; HPF: High Power Field (magnification x250).