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. Author manuscript; available in PMC: 2021 Sep 15.
Published in final edited form as: Acta Biomater. 2020 Jul 8;114:407–420. doi: 10.1016/j.actbio.2020.07.006

Fig. 3.

Fig. 3

(A) At pH 5.0, the isoflavones primarily stay in partially protonated form resulting in lower solubility. (B) In vitro cumulative release of genistein in single and combined form fitted in Korsmeyer-Peppas model at pH 5.0. Increased genistein release can be seen in single drug delivery compared to the combination form. (C) In vitro cumulative release of daidzein fitted in Korsmeyer-Peppas model showing increased in vitro release in the presence of a second drug in the system, unlike the other two isoflavones. (D) In vitro cumulative release of glycitein fitted in Korsmeyer-Peppas model showing lower cumulative release compared to single glycitein delivery.