Table 1.
Baseline Demographics and Clinical Characteristics
| Total (N=518) | ||
|---|---|---|
| Age, years | Mean (SD) | 37.3 (11.2) |
| Sex, n (%) | Female | 288 (55.6) |
| Education status, n (%) | University degree or higher | 250 (48.3) |
| Up to and including junior college graduate level | 268 (51.7) | |
| Employment status, n (%) | Employed/self-employed | 437 (84.4) |
| Full-time | 386 (88.3)a | |
| Part-time | 51 (11.7)a | |
| Other (unemployed, student, etc.) | 81 (15.6) | |
| History of MDD episodes, n (%) | First episode | 310 (59.8) |
| Relapse | 208 (40.2) | |
| If relapsed, onset time of previous depressive episode, n (%) | Within the last 12 months | 39 (18.8)b |
| Earlier in life | 169 (81.3)b | |
| Time since onset of current depressive episode, n (%) | <8 weeks | 170 (32.8) |
| ≥8 weeks | 348 (67.2) | |
| Antidepressant prescribed at baseline, n (%) | Tricyclic | 31 (6.0) |
| SSRI | 209 (40.3) | |
| SNRI | 174 (33.6) | |
| NaSSA | 61 (11.8) | |
| Other | 43 (8.3) |
Notes: aDenominator is 437 patients in paid employment or self-employed. Full-time was defined as working more than 32 hours per week. bDenominator is 208 patients with relapsed MDD. Adapted from J Affect Disord, Vol 258, Sumiyoshi T, Watanabe K, Noto S, et al. “Relationship of cognitive impairment with psychosocial function and relapse of depressive symptoms in patients with major depressive disorder: Analysis of longitudinal data from PERFORM-J”, 172–178, Copyright (2019), with permission from Elsevier.20
Abbreviations: MDD, major depressive disorder; NaSSA, noradrenergic and specific serotonergic antidepressant; SD, standard deviation; SNRI, serotonin–norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor.