Table 3.
Relapse Rate at 6 Months by Degree of Cognitive Function, as Assessed by DSST and PDQ-D at 2 Months
| n | Relapse at 6 Months, n (%) | Multivariate Logistic Regression Analysis | ||
|---|---|---|---|---|
| Odds Ratio (95% CI) | p value | |||
| DSST total score (2 months) | ||||
| Within norm | 87 | 14 (16.1) | 1 | |
| 1/3 to 2/3 SD below norm | 22 | 3 (13.6) | 0.73 (0.17, 3.12) | 0.670 |
| 2/3 to 1 SD below norm | 24 | 4 (16.7) | 0.73 (0.17, 3.02) | 0.659 |
| 1 SD or more below norm | 54 | 7 (13.0) | 0.92 (0.30, 2.78) | 0.883 |
| PDQ-D total score (2 months) | ||||
| 0–10 | 70 | 4 (5.7) | 1 | |
| 11–18 | 58 | 7 (12.1) | 2.13 (0.53, 8.58) | 0.286 |
| 19–30 | 41 | 11 (26.8) | 4.72 (1.25, 17.90) | 0.022 |
| 31–80 | 17 | 6 (35.3) | 4.95 (0.93, 26.45) | 0.061 |
Notes: The following factors were used in multivariate logistic regression analysis: baseline age, sex, educational level, time since start of current depressive episode, concomitant mental disorders, comorbid somatic conditions, chronic pain, MADRS, and DSST/PDQ-D total scores at 2 months.
Abbreviations: CI, confidence interval; DSST, Digital Symbol Substitution Test; MADRS, Montgomery–Åsberg Depression Rating Scale; PDQ-D, Patient Deficit Questionnaire–Depression; SD, standard deviation.