Skip to main content
. 2021 Mar 17;10:e65453. doi: 10.7554/eLife.65453

Figure 2. SARS-CoV-2 viral genomes are more similar in groups of patients and healthcare workers (HCWs) who have been in contact prior to a positive SARS-CoV-2 test.

Figure 2.

(a) Pairwise genomic variant similarity comparisons of SARS-CoV-2 genomes by the status within patient contact clusters (PCCs) demonstrates increased genetic similarity when patients have been in direct or indirect contact with one another 3–7 days prior to positive SARS-CoV-2 test. Pairwise comparisons within PCCs (n = 544) were tested against all pairwise comparisons that were not defined within the PCCs (n = 29,212). (b) Pairwise genomic variant similarity comparisons of SARS-CoV-2 genomes by patient–HCW interactions in the week prior to positive SARS-CoV-2 test (n, yes = 98, no = 11,836). (c) Pairwise genomic variant similarity comparisons of SARS-CoV-2 genomes by presence within PCCs including interactions with HCWs. Pairwise comparisons within HCW clusters (n = 846) were tested against pairwise comparisons that were not defined within the PCCs including HCW interactions (n = 28,168). Colours of boxplots reflect the PCCs identified in Figure 1, and asterisks indicate significance level determined through a two-sided Wilcoxon rank-sum test (*<0.05; **<0.01; ***<0.001 after Bonferroni correction for multiple testing).