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| kon,1 (M−1 s−1) | koff,1 (s−1) | Kd,1 (nM) | kon,2 (M−1 s−1) | koff,2 (s−1) | Kd,2 (nM) | |
|---|---|---|---|---|---|---|
| H1 (two site) | (1.5 ± 0.6) × 109 | 40 ± 5 | 27* | (3.7 ± 1.3) × 108 | 16 ± 3 | 42* |
| H2 (one site) | (1.6 ± 0.1) × 108 | 2600 ± 100 | 16000 ± 1000 | – | – | – |
*Kds taken from ITC analysis, kept constant during fitting.
NMR: nuclear magnetic resonance; ITC: isothermal titration calorimetry.
