Author response image 5. Comparison of results from our EWAS meta-analysis (x-axis) with those identified in an analysis of human PFC (y-axis).

Overall there is a significant enrichment of consistent results between the analyses for SZ-associated DMPs. Black dots represent DMPs that we found to show low covariation (r < 0.2) between blood and cortex tissue in a previous analysis of matched samples from the same individuals (Hannon et al., Epigenetics, PMID: 26457534), with blue (r > 0.2) and red (r > 0.5) symbols highlighting sites with stronger covariation in DNAm between tissues.