Table 2.
Fibroid and birth outcomes adjusting for age and BMI (n = 3848)*
| Fibroid characteristic | n (%)† | Birthweight (grams) | Gestational age (d) | ||
|---|---|---|---|---|---|
| Model 1 Coefficient (95% CI) | Model 2 Coefficient (95% CI) | Model 1 Coefficient (95% CI) | Model 2 Coefficient (95% CI) | ||
| Fibroids present | |||||
| No | 3510 (89.4) | 0 (Reference) | 0 (Reference) | 0 (Reference) | 0 (Reference) |
| Yes | 416 (10.6) | −86 (−143, −29) | −20 (−77, 36) | −0.2 (−1.6, 1.1) | 0.4 (−0.9, 1.8) |
| Fibroid number‡ | |||||
| 1 | 294 (70.7) | −33 (−99, 33) | 12 (−53, 77) | 0.6 (−1.0, 2.2) | 1.1 (−0.6, 2.7) |
| 2 | 65 (15.6) | −104 (−239, 31) | −22 (−155, 111) | −1.2 (−4.4, 2.0) | −0.4 (−3.5, 2.8) |
| ≥3 | 57 (13.7) | −353 (−497, −208) | −201 (−345, −58) | −3.8 (−7.3, −0.4 | −2.1 (−5.5, 1.3) |
| Fibroid type‡,§ | |||||
| Any subserosal | 173 (41.6) | −115 (−200, −30) | −39 (−122, 45) | −1.1 (−3.1, 0.9) | −0.2 (−2.2, 1.8) |
| Any intramural | 186 (44.7) | −119 (−201, −38) | −47 (−128, 33) | −0.1 (−2.0, 1.8) | 0.7 (−1.2, 2.6) |
| Any submucosal | 82 (19.7) | −86 (−205, 32) | 24 (−93, 141) | −0.1 (−2.9, 2.7) | 1.0 (−1.8, 3.8) |
| Missing | 13 | ||||
| Total volume‡,∥ | |||||
| Lowest quartile | 102 (24.5) | 44 (−63, 151) | 72 (−33, 177) | 1.5 (−1.1, 4.0) | 1.7 (−0.8, 4.2) |
| 2nd quartile | 102 (24.5) | −162 (−271, −54) | −109 (−215, −3) | −0.9 (−3.5, 1.7) | 0.0 (−2.8, 2.3) |
| 3rd quartile | 106 (25.5) | −32 (−139, 75) | 31 (−74, 136) | 0.2 (−2.3, 2.7) | 0.9 (−1.7, 3.4) |
| Top quartile | 105 (25.2) | −190 (−298, −83) | −73 (−179, 34) | −1.7 (−4.3, 0.8) | −0.5 (−3.0, 2.1) |
| Missing | 1 | ||||
Abbreviations: BMI = body mass index; CI = confidence interval.
*
Model 1 adjusts for age and BMI; 78 participants missing confounder data were excluded. Model 2 adjusts for age, BMI, and race or ethnicity; 81 participants missing confounder data were excluded.
†
Data are counts and column percentages for each characteristic for model 1. Percentages exclude missing data.
‡
Only available for women with fibroids.
§
Type is mutually exclusive for each fibroid, but a woman with multiple fibroids can have more than one type of fibroid.
∥
Quartiles for total fibroid volume (cm3): <0.92, 0.92–4.54, 4.55–19.47, >19.47.