Skip to main content
. 2021 Mar 23;2021:6657206. doi: 10.1155/2021/6657206

Figure 5.

Figure 5

EGB761 reduced the accumulation of ECM and the expression of EMT markers in HK-2 cells via the inhibition of ERS. (a) Western blot of α-SMA and E-cadherin. (b) Bar graph representing the quantification of α-SMA, and bar graph representing the quantification of α-SMA and E-cadherin. (b) The mRNA expression of α-SMA and E-cadherin. (c) Western blot of collagen IV, fibronectin, and bar graph representing the quantification of collagen IV and fibronectin. (d) The mRNA expression of collagen IV and fibronectin. Ctrl: control treated with PBS; TM: tunicamycin; TM+4-PBA: tunicamycin+4-PBA; TM + MD: tunicamycin+EGB761 20 mg/L. Results are expressed as mean ± SD. ∗P < 0.05, ∗∗P < 0.01 versus Ctrl. #P < 0.05, ##P < 0.01 versus TM.