. 2021 Mar 23;2021:6674658. doi: 10.1155/2021/6674658

Table 3.

Comparison according to POMS (1/2).

Items	Time	Ketamine (N = 30)	Control (N = 30)	Effect of ketamine relative to control		RMANOVA P values
Items	Time	Ketamine (N = 30)	Control (N = 30)	Mean ± SD	Between subjects	Between subjects	Within subjects	Inter-action
Vigor
Active	Pre	1.0 ± 0.5	1.1 ± 0.5	−0.1 ± 0.1	−0.3–0.2	0.203	<0.001 ^{^∗}	0.004 ^{^∗}
Active	Post	2.2 ± 0.6	1.8 ± 0.6	0.4 ± 0.2	0.1–0.7	0.203	<0.001 ^{^∗}	0.004 ^{^∗}
Alert	Pre	1.4 ± 0.8	1.5 ± 0.9	−0.1 ± 0.2	−0.5–0.4	0.139	0.005 ^{^{^∗}}	0.041 ^{^∗}
Alert	Post	2.2 ± 1.0	1.6 ± 1.0	0.6 ± 0.3	0.1–1.1	0.139	0.005 ^{^{^∗}}	0.041 ^{^∗}
Energetic	Pre	0.8 ± 0.6	0.7 ± 0.7	0.2 ± 0.2	−0.2–0.5	0.047 ^{^∗}	<0.001 ^{^∗}	0.010 ^{^∗}
Energetic	Post	2.2 ± 0.8	1.5 ± 1.2	0.7 ± 0.3	0.1–1.2	0.047 ^{^∗}	<0.001 ^{^∗}	0.010 ^{^∗}
Lively	Pre	0.3 ± 0.5	0.1 ± 0.4	0.1 ± 0.1	−0.1–0.4	0.300	<0.001 ^{^∗}	0.999
Lively	Post	0.7 ± 0.6	0.5 ± 0.7	0.1 ± 0.2	−0.2–0.5	0.300	<0.001 ^{^∗}	0.999
Total vigor subscale	Pre	3.5 ± 1.3	3.4 ± 1.8	0.2 ± 0.4	−0.6–1.0	0.042 ^{^∗}	<0.001 ^{^∗}	0.004 ^{^∗}
Total vigor subscale	Post	7.2 ± 2.2	5.4 ± 2.8	1.8 ± 0.7	0.5–3.1	0.042 ^{^∗}	<0.001 ^{^∗}	0.004 ^{^∗}

Tension
Anxious	Pre	1.7 ± 0.5	1.4 ± 1.0	0.3 ± 0.2	−0.1–0.7	0.049 ^{^∗}	0.869	<0.001 ^{^∗}
Anxious	Post	1.0 ± 0.7	2.0 ± 0.9	−1.0 ± 0.2	−1.4–0.6	0.049 ^{^∗}	0.869	<0.001 ^{^∗}
Nervous	Pre	1.3 ± 0.7	1.2 ± 0.9	0.1 ± 0.2	−0.3–0.5	0.001 ^{^∗}	0.489	<0.001 ^{^∗}
Nervous	Post	0.5 ± 0.6	1.8 ± 1.1	−1.3 ± 0.2	−1.8–0.9	0.001 ^{^∗}	0.489	<0.001 ^{^∗}
Panicky	Pre	1.2 ± 1.1	1.4 ± 0.9	−0.2 ± 0.3	−0.7–0.3	<0.001 ^{^∗}	0.359	<0.001 ^{^∗}
Panicky	Post	0.4 ± 0.5	2.0 ± 1.0	−1.6 ± 0.2	−2.0–1.2	<0.001 ^{^∗}	0.359	<0.001 ^{^∗}
Worried	Pre	1.6 ± 0.8	1.6 ± 1.0	0.0 ± 0.2	−0.5–0.4	<0.001 ^{^∗}	0.237	<0.001 ^{^∗}
Worried	Post	0.7 ± 0.6	2.2 ± 1.0	−1.5 ± 0.2	−1.9–1.0	<0.001 ^{^∗}	0.237	<0.001 ^{^∗}
Total tension subscale	Pre	5.8 ± 1.9	5.6 ± 2.1	0.2 ± 0.5	−0.8–1.3	<0.001 ^{^∗}	0.099	<0.001 ^{^∗}
Total tension subscale	Post	2.6 ± 1.5	8.0 ± 2.3	−5.4 ± 0.5	−6.4–4.4	<0.001 ^{^∗}	0.099	<0.001 ^{^∗}

Fatigue
Exhausted	Pre	1.3 ± 0.5	1.5 ± 1.2	−0.2 ± 0.2	−0.7–0.3	<0.001 ^{^∗}	<0.001 ^{^∗}	<0.001 ^{^∗}
Exhausted	Post	1.0 ± 0.4	2.6 ± 1.2	−1.7 ± 0.2	−2.1–1.2	<0.001 ^{^∗}	<0.001 ^{^∗}	<0.001 ^{^∗}
Sleepy	Pre	1.3 ± 0.7	1.2 ± 0.9	0.1 ± 0.2	−0.3–0.5	0.358	<0.001 ^{^∗}	0.053
Sleepy	Post	1.7 ± 0.6	2.1 ± 1.1	−0.4 ± 0.2	−0.9–0.1	0.358	<0.001 ^{^∗}	0.053
Tired	Pre	2.1 ± 0.8	1.9 ± 1.0	0.1 ± 0.2	−0.3–0.6	<0.001 ^{^∗}	0.110	<0.001 ^{^∗}
Tired	Post	0.8 ± 0.5	2.8 ± 1.0	−2.0 ± 0.2	−2.4–1.5	<0.001 ^{^∗}	0.110	<0.001 ^{^∗}
Worn out	Pre	1.0 ± 0.8	1.1 ± 0.9	−0.2 ± 0.2	−0.6–0.3	<0.001 ^{^∗}	<0.001 ^{^∗}	<0.001 ^{^∗}
Worn out	Post	0.3 ± 0.5	2.5 ± 1.3	−2.2 ± 0.2	−2.7–1.7	<0.001 ^{^∗}	<0.001 ^{^∗}	<0.001 ^{^∗}
Total fatigue subscale	Pre	5.6 ± 1.8	5.8 ± 2.6	−0.2 ± 0.6	−1.3–1.0	<0.001 ^{^∗}	<0.001 ^{^∗}	<0.001 ^{^∗}
Total fatigue subscale	Post	3.7 ± 1.0	10.0 ± 3.8	−6.2 ± 0.7	−7.7–4.8	<0.001 ^{^∗}	<0.001 ^{^∗}	<0.001 ^{^∗}

^∧RMANOVA test. ^{^∗}Significant.