Table 5.
Variables | Ketamine (N = 30) | Control (N = 30) | P value | Effect of ketamine relative to control | ||
---|---|---|---|---|---|---|
Mean ± SD | 95% CI | |||||
Postoperative sedation | ||||||
Minute 0 | 1.3 ± 0.5 | 0.3 ± 0.5 | ∧<0.001 ∗ | 1.0 ± 0.1 | 0.8–1.2 | |
Minute 60 | 0.2 ± 0.4 | 0.0 ± 0.0 | ∧0.023 ∗ | 0.2 ± 0.1 | 0.0–0.3 | |
Minute 120 | 0.1 ± 0.3 | 0.0 ± 0.0 | ∧0.155 | 0.1 ± 0.0 | 0.0–0.2 | |
| ||||||
Satisfaction | ||||||
Satisfaction | 1.6 ± 0.5 | 2.8 ± 0.8 | ∧<0.001 ∗ | -1.2 ± 0.2 | −1.5–0.8 | |
| ||||||
Perioperative side effects | ||||||
RR (95% CI) | ||||||
Headache | Intraoperative | 6 (20.0%) | 0 (0.0%) | §0.024 ∗ | — | |
Postoperative | 7 (23.3%) | 6 (20.0%) | #0.754 | 1.17 (0.44–3.07) | ||
Diplopia | Intraoperative | 9 (30.0%) | 0 (0.0%) | §0.002 ∗ | — | |
Postoperative | 6 (20.0%) | 0 (0.0%) | §0.024 ∗ | — | ||
| ||||||
Perioperative psychedelic phenomena | ||||||
Hallucination | 2 (6.7%) | 0 (0.0%) | §0.492 | — | ||
Dissociation | 6 (20.0%) | 0 (0.0%) | §0.024 ∗ | — | ||
Relaxation | 25 (83.3%) | 0 (0.0%) | #<0.001 ∗ | — | ||
Euphoria | 7 (23.3%) | 0 (0.0%) | §0.011 ∗ | — | ||
Dysphoria | 1 (3.3%) | 0 (0.0%) | §0.999 | — |
∧Independent t-test. #Chi square test. §Fisher's Exact test. ∗Significant. RR: relative risk. CI: confidence interval. ∗Significant.