Table 3.
Pregnancy outcome of infants affected with CDH according to clinical presentation 2001–2012.
| Country- Registry | Isolated CDH | MCA CDH | Syndromic CDH | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Cases | Pregnancy Outcome | Total Cases | Pregnancy Outcome | Total Cases | Pregnancy Outcome | ||||||||||||
| N | % | LB % | SB % | ETOPFA % | N | % | LB % | SB % | ETOPFA % | N | % | LB % | SB % | ETOPFA % | |||
| Hospital-Based Registries | |||||||||||||||||
| Argentina-RENAC1 | 100 | 71.9% | 99.0% | 1.0% | 0.0% | 35 | 25.2% | 91.4% | 8.6% | 0.0% | 4 | 2.9% | 50.0% | 50.0% | 0.0% | ||
| Colombia-Bogotá2 | 58 | 80.6% | 98.3% | 1.7% | 0.0% | 12 | 16.7% | 91.7% | 8.3% | 0.0% | 2 | 2.7% | 100.0% | 0.0% | 0.0% | ||
| SA-ECLAMC1,3 | 443 | 61.9% | 91.5% | 2.5% | 0.0% | 273 | 38.1% | 84.6% | 15.4% | 0.0% | - | - | - | - | - | ||
| Spain-ECEMC | 84 | 64.6% | 75.0% | 0.0% | 25.0% | 32 | 24.6% | 68.8% | 6.2% | 25.0% | 14 | 10.8% | 64.3% | 7.1% | 28.6% | ||
| Mexico-RYVEMCE1 | 19 | 63.3% | 89.5% | 10.5% | 0.0% | 8 | 26.7% | 87.5% | 12.5% | 0.0% | 3 | 10.0% | 100.0% | 0.0% | 0.0% | ||
| Israel-SMC4 | 36 | 92.7% | 100.0% | 0.0% | 0.0% | 3 | 7.3% | 100.0% | 0.0% | 0.0% | 0 | 0.0% | 0.0% | 0.0% | 0.0% | ||
| TOTAL | 740 | 65.7% | 95.1% | 2.0% | 2.9% | 363 | 32.2% | 84.3% | 13.5% | 2.2% | 23 | 2.1% | 69.6% | 13.0% | 17.4% | ||
| Population-Based Registries | |||||||||||||||||
| Costa Rica-CREC1,5 | 95 | 69.3% | 100.0% | 0.0% | 0.0% | - | - | - | - | - | - | - | - | - | - | ||
| Czech Republic6 | - | - | - | - | - | - | - | - | - | - | 7 | 2.1% | 57.1% | 0.0% | 42.9% | ||
| France-Paris | 53 | 62.4% | 86.8% | 1.9% | 11.3% | 18 | 21.2% | 50.0% | 0.0% | 50% | 14 | 16.4% | 14.3% | 7.1% | 78.6% | ||
| Germany-Saxony Anhalt | 37 | 63.8% | 89.2% | 2.7% | 8.1% | 14 | 24.1% | 50.0% | 0.0% | 50% | 7 | 12.1% | 57.1% | 14.3% | 28.6% | ||
| Italy-Lombardy | 16 | 43.2% | 81.3% | 12.5% | 6.2% | 21 | 52.5% | 57.1% | 19.0% | 23.8% | 3 | 7.5% | 33.3% | 0.0% | 66.7% | ||
| Malta-MCAR1 | 17 | 65.4% | 94.1% | 5.9% | 0.0% | 6 | 23.1% | 100.0% | 0.0% | 0.0% | 3 | 11.5% | 66.7% | 33.3% | 0.0% | ||
| Netherlands-Northern | 41 | 68.3% | 82.9% | 7.3% | 9.8% | 8 | 13.3% | 62.5% | 12.5% | 25% | 11 | 18.4% | 54.5% | 18.2% | 27.3% | ||
| Slovak Republic3 | 81 | 68.1% | 97.6% | 1.2% | 1.2% | 38 | 31.9% | 97.4% | 2.6% | 0.0% | - | - | - | - | - | ||
| Sweden | 224 | 56.4% | 83.5% | 0.9% | 15.6% | 137 | 34.5% | 62.0% | 1.5% | 36.5% | 36 | 9.1% | 16.6% | 2.8% | 80.6% | ||
| Ukraine-OMNI-Net | 68 | 64.8% | 64.7% | 13.2% | 20.6% | 33 | 31.4% | 45.4% | 24.2% | 24.2% | 4 | 3.8% | 75.0% | 0.0% | 25.0% | ||
| United Kingdom-Wales | 86 | 54.0% | 82.5% | 1.2% | 16.3% | 47 | 29.6% | 72.3% | 0.0% | 27.7% | 26 | 16.4% | 50.0% | 0.0% | 50.0% | ||
| USA-Utah | 132 | 60.8% | 96.2% | 2.3% | 1.5% | 59 | 27.2% | 88.1% | 10.2% | 1.7% | 26 | 12.0% | 73.1% | 15.4% | 11.5% | ||
| TOTAL | 850 | 62.1% | 87.6% | 2.8% | 9.4% | 381 | 27.9% | 68.8% | 5.8% | 24.9% | 137 | 10.0% | 43.8% | 7.3% | 48.9% | ||
| ALL REGISTRIES | 1,590 | 63.8% | 91.1% | 2.5% | 6.4% | 744 | 29.8% | 76.3% | 9.5% | 13.8% | 160 | 6.4% | 47.5% | 8.1% | 44.4% | ||
ETOPFA not allowed
ETOPFA not registered
data only provided for isolated and MCA cases
data on live born children with congenital diaphragmatic hernia from one hospital
data only provided for isolated cases
data only provided for syndromic cases.
CREC=Costa Rican Birth Defect Registry; ECEMC=Spanish Collaborative Study of Congenital Malformations; ECLAMC=Latin American Collaborative Study of Congenital Malformations; ETOPFA=Elective Termination of Pregnancy for Fetal Anomalies; LB=Live Birth; MCA=Multiple Congenital Anomalies; MCAR=Malta Congenital Anomalies Registry; OMNI-Net=Ukraine Birth Defects Prevention Program; RENAC=National Network of Congenital Anomalies of Argentina; RYVEMCE=Mexican Registry and Epidemiological Surveillance of External Congenital Malformations; SA=South America; SB=Stillbirth; SMC=Soroka Medical Center; TROCA=Tabriz Registry of Congenital Anomalies; USA=United States of America.