Table 4.

Two-way sensitivity analysis varying duration of treatment effect and utility values

Duration of treatment effect, in years	Proxy utility assessment using EQ-5D-5L in same patient population (source Lloyd et al. 2019 [18]) (€)	Proxy utility assessment using HUI-3 in same patient population (source Lloyd et al. 2019 [18]) (€)	Direct utility assessment with TTO in different patient population (source Brown et al. 1999 [17]) (€)
10 + 10 waning	115,673	131,147	184,417
20	80,994	91,445	128,368
40	54,310	61,002	85,873
70 (± life-long)	47,239	52,628	74,325

HUI Health Utility Index, TTO time trade-off