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10 of the 12 SIV-infected macaques had lower corneal nerve fiber counts 10 days post-inoculation with SIV than their baseline pre-infection corneal scan values (left panel; P = 0.01, paired t-test). Similarly, fractal dimension declined with SIV infection in of 12 animals (middle panel; P = 0.008, paired t-test). In contrast, tortuosity was not altered during acute infection (right panel).
