Table 2.
Summary of performances of estimates from different methods when data is simulated from a JLCM with opposite covariate effects on recurrence and termination risks: RB is the relative bias, SD is the average posterior Standard-Deviation, and RMSE is the square-root of mean square error based on 500 replicates.
| n=100 | n=400 | ||||||
|---|---|---|---|---|---|---|---|
| Methods | Parameter | RB | SD | RMSE | RB | SD | RMSE |
| JLCM with uniform prior for η | α | −0.034 | 0.423 | 0.017 | −0.009 | 0.311 | 0.011 |
| β | 0.004 | 0.174 | 0.004 | 0.004 | 0.151 | 0.003 | |
| γ | 0.066 | 0.284 | 0.066 | 0.047 | 0.236 | 0.044 | |
| η1 | 0.035 | 0.230 | 0.014 | 0.008 | 0.222 | 0.009 | |
| η2 | 0.033 | 0.373 | 0.026 | 0.005 | 0.364 | 0.015 | |
| K | 0.150 | 0.813 | 0.300 | 0.114 | 0.747 | 0.280 | |
| JLCM with Cauchy prior for η | α | −0.076 | 0.411 | 0.038 | −0.026 | 0.330 | 0.033 |
| β | −0.050 | 0.166 | 0.050 | −0.016 | 0.136 | 0.034 | |
| γ | 0.068 | 0.283 | 0.068 | 0.051 | 0.256 | 0.062 | |
| η1 | −0.938 | 0.031 | 0.375 | −0.653 | 0.013 | 0.328 | |
| η2 | −0.895 | 0.096 | 0.716 | −0.613 | 0.018 | 0.686 | |
| K | 0.923 | 0.333 | 1.846 | 0.935 | 0.313 | 1.548 | |
| Shared-frailty Model | β | −0.049 | 0.218 | 0.222 | −0.024 | 0.217 | 0.197 |
| γ | 0.186 | 0.327 | 0.375 | 0.173 | 0.259 | 0.376 | |