Table 3.
Adjusted Hazard Ratios of BMI Trajectories (Ages 31-80) from Cox Hazard Models in Framingham Heart Study Offspring Cohort 1979-2001.
| Number of Persons | Number of Deaths | Birth Cohorts and Gender Adjusted | Education Adjusteda | Behavioral Factors Adjustedb | Fully Adjustedc | |
|---|---|---|---|---|---|---|
| HR (95 % CI) | HR (95 % CI) | HR (95 % CI) | HR (95 % CI) | |||
| Body mass index trajectories | ||||||
| Lower level of normal weightd | 325 | 98 | 1.36 (1.07, 1.73) | 1.43 (1.13, 1.83) | 1.24 (0.97, 1.59) | 1.26 (0.99, 1.61) |
| Normal weightd stable | 927 | 251 | 1.05 (0.89, 1.25) | 1.09 (0.92, 1.30) | 1.04 (0.88, 1.24) | 1.05 (0.89, 1.25) |
| Normal weightd upward | 1,113 | 293 | 1.00 | 1.00 | 1.00 | 1.00 |
| Overweighte obesity | 867 | 194 | 1.01 (0.84, 1.21) | 1.02 (0.85, 1.22) | 1.01 (0.84, 1.21) | 1.00 (0.84, 1.20) |
| Class I obesef | 402 | 105 | 1.47 (1.19, 1.82) | 1.42 (1.14, 1.76) | 1.43 (1.15, 1.77) | 1.41 (1.14, 1.75) |
| Class II/III obeseg | 119 | 26 | 1.84 (1.24, 2.74) | 1.70 (1.14, 2.55) | 1.79 (1.21, 2.64) | 1.71 (1.16, 2.54) |
| AIC | 13,858.68 | 13,828.27 | 13,713.75 | 13,703.77 | ||
| BIC | 13,917.17 | 13,901.38 | 13,801.49 | 13,796.38 | ||
| Observations | 19,067 | 19,067 | 19,067 | 19,067 | ||
a
Adjusted for birth cohorts, gender, and education
b
Adjusted for birth cohorts, gender, education, and smoking behavior
c
Adjusted for birth cohorts, gender, education, smoking behavior, and disease index
d
Normal weight was defined as having a BMI between 18.5 and 24.9 kg/m2
e
Overweight was defined as having a BMI between 25 and 29.9 kg/m2
f
Class I obesity was defined as having a BMI between 30 and 34.9 kg/m2
g
Class II/III obesity was defined as having a BMI greater than or equal to 35 kg/m2