Table 4.
Associations (Spearman correlation coefficient (p-value)) between period-specific fluoride intake (AUC) and MDCT-derived trabecular and cortical bone measures.
| Bone Measures (units) | Daily Fluoride Intake | |||||||
|---|---|---|---|---|---|---|---|---|
| Females | Males | |||||||
| mg F 0-8.5 years (n=160) | mg F 8.5-14 years (n=149) | mg F 14-19 years (n=137) | mg F 0-19 years (n=143) | mg F 0-8.5 years (n=135) | mg F 8.5-14 years (n=123) | mg F 14-19 years (n=107) | mg F 0-19 years (n=113) | |
| Trabecular (Tb) | ||||||||
| Tb.vBMD (mg/cc) | 0.02 (0.82) | 0.00 (1.00) | 0.08 (0.36) | 0.06 (0.48) | 0.10 (0.25) | 0.04 (0.64) | 0.05 (0.60) | 0.11 (0.23) |
| Tb.tBMD (mg/cc) | 0.03 (0.73) | 0.00 (0.97) | 0.10 (0.25) | 0.07 (0.38) | 0.09 (0.29) | 0.05 (0.58) | 0.04 (0.68) | 0.12 (0.21) |
| Tb.pBMD (mg/cc) | −0.01 (0.88) | 0.07 (0.40) | 0.16 (0.07) | 0.13 (0.13) | 0.05 (0.54) | 0.00 (0.99) | 0.07 (0.46) | 0.09 (0.33) |
| Tb.NA (cm2/cm3) | −0.04 (0.63) | 0.02 (0.77) | 0.17 (0.05) | 0.10 (0.26) | 0.11 (0.20) | 0.03 (0.72) | 0.08 (0.42) | 0.17 (0.07) |
| Tb.PW (μm) | −0.00 (0.97) | 0.08 (0.31) | 0.18 (0.03)* | 0.16 (0.05) | 0.05 (0.58) | 0.01 (0.95) | 0.07 (0.45) | 0.10 (0.29) |
| Tb.Th (μm) | −0.03 (0.71) | 0.09 (0.29) | 0.20 (0.02)* | 0.16 (0.05) | 0.04 (0.68) | −0.01 (0.94) | 0.05 (0.60) | 0.06 (0.50) |
| Tb.Sp (μm) | −0.03 (0.72) | 0.03 (0.75) | −0.03 (0.75) | −0.02 (0.81) | −0.13 (0.12) | −0.10 (0.27) | −0.05 (0.60) | −0.15 (0.11) |
| Cortical (Cb) | ||||||||
| Cb.Poro (no unit) | 0.03 (0.68) | 0.04 (0.60) | 0.01 (0.91) | 0.02 (0.82) | 0.09 (0.32) | 0.08 (0.36) | 0.07 (0.49) | 0.07 (0.47) |
| Cb.Th (μm) | −0.13 (0.09) | −0.01 (0.88) | 0.11 (0.18) | 0.01 (0.87) | −0.08 (0.36) | −0.05 (0.60) | 0.02 (0.88) | −0.02 (0.85) |
*
Suggestive (0.01<p-value <0.05).
Tb.vBMD: volumetric BMD, Tb.tBMD: transpose BMD, Tb.pBMD: plate trabecula BMD, Tb.NA: trabecular network, Tb.PW: plate width, Tb.Th: trabecular thickness, Tb.Sp: trabecular spacing, Cb.Poro: cortical porosity, Cb.Th: cortical thickness.
F = fluoride