Table 5.
Adjusted associations between period-specific fluoride intakes and MDCT-derived bone measures (Partial Spearman correlation coefficient (p-value) with height, weight, years since age of peak height velocity (PHV), calcium and protein intakes, Healthy Eating Index version 2010 (HEI-2010), and PAQ-score as covariates).
| Bone Measures (units) | Daily Fluoride Intake | |||||||
|---|---|---|---|---|---|---|---|---|
| Females | Males | |||||||
| mg F 0-8.5 years (n=155) | mg F 8.5-14 years (n=144) | mg F 14-19 years (n=134) | mg F 0-19 years (n=141) | mg F 0-8.5 years (n=126) | mg F 8.5-14 years (n=114) | mg F 14-19 years (n=99) | mg F 0-19 years (n=105) | |
| Trabecular (Tb) | ||||||||
| Tb.vBMD (mg/cc) | 0.02 (0.85) | −0.02 (0.82) | 0.01 (0.89) | 0.02 (0.85) | 0.01 (0.89) | −0.02 (0.87) | −0.05 (0.61) | 0.04 (0.72) |
| Tb.tBMD (mg/cc) | 0.02 (0.77) | −0.01 (0.87) | 0.04 (0.65) | 0.03 (0.69) | 0.01 (0.93) | −0.00 (0.96) | −0.06 (0.55) | 0.05 (0.63) |
| Tb.pBMD (mg/cc) | −0.01 (0.91) | 0.05 (0.54) | 0.12 (0.18) | 0.10 (0.24) | 0.00 (0.99) | −0.02 (0.82) | 0.01 (0.90) | 0.08 (0.44) |
| Tb.NA (cm2/cm3) | −0.05 (0.57) | −0.01 (0.95) | 0.12 (0.19) | 0.05 (0.54) | 0.02 (0.83) | −0.02 (0.82) | −0.03 (0.81) | 0.12 (0.25) |
| Tb.PW (μm) | −0.00 (0.96) | 0.07 (0.39) | 0.14 (0.12) | 0.14 (0.11) | −0.01 (0.88) | −0.04 (0.69) | 0.01 (0.90) | 0.07 (0.48) |
| Tb.Th (μm) | −0.02 (0.77) | 0.09 (0.31) | 0.18 (0.04)* | 0.16 (0.07) | −0.02 (0.86) | −0.0 2(0.80) | 0.01 (0.92) | 0.0 5(0.61) |
| Tb.Sp (μm) | −0.02 (0.84) | 0.06 (0.47) | 0.05 (0.60) | 0.04 (0.64) | −0.04 (0.64) | −0.04 (0.67) | 0.06 (0.56) | −0.06 (0.56) |
| Cortical (Cb) | ||||||||
| Cb.Poro (no unit) | −0.02 (0.83) | −0.01 (0.95) | −0.08 (0.35) | −0.04 (0.64) | 0.01 (0.92) | 0.03 (0.73) | 0.03 (0.81) | −0.01(0.91) |
| Cb.Th (μm) | −0.12 (0.13) | 0.01 (0.90) | 0.10 (0.25) | −0.01 (0.91) | −0.12 (0.20) | 0.01 (0.94) | −0.02 (0.83) | −0.05 (0.61) |
*
Suggestive (0.01 < p-value < 0.05).
Tb.vBMD: volumetric BMD, Tb.tBMD: transpose BMD, Tb.pBMD: plate trabecula BMD, Tb.NA: trabecular network, Tb.PW: plate width, Tb.Th: trabecular thickness, Tb.Sp: trabecular spacing, Cb.Poro: cortical porosity, Cb.Th: cortical thickness.
F = fluoride