Scheme 4. Synthesis of 38 *.
* Reagents and conditions: (a) A7, NaH, THF, reflux, 2.5 h (42%); (b) 2-Cl-4-MePhB(OH)2, Pd(PPh3)4, Na2CO3, DMF, ACN, 90 °C, 5 h (57%); (c) m-CPBA, DCM, rt, 5 h (68%); (d) A13c, NaH, THF, DMF, 0 °C to rt, 2.5 h (75%).
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