Figure 6.

Renal pyruvate uptake and metabolism were imaged in healthy BALB/c mice using spectral-spatial excitation (upper panels) and multi-excitation CSE (lower panels). HP images in the central panel are bilinearly interpolated to the resolution of the axial proton images (lower left) and averaged over time. Native resolution voxels containing a large blood vessel and kidney parenchyma are outlined in green and purple, respectively. The HP signals for these vascular and renal voxels are plotted overtime on the right, and the shaded portions of these plots indicate the time points averaged in the HP images. All images depict a 4x4 cm² FOV.