Table 2.
Subcortical volumetric results
| S-W p values | M-W/t-test | ||||
|---|---|---|---|---|---|
| Volume (mm3) | Control (N = 37) | PD (N = 48) | Control | PD | p values |
| Total intracranial | 1,519,807 ± 170,334 | 1,592,940 ± 153,488 | 0.163 | 0.985 | 0.041 |
| Thalamus | 6,851 ± 775 | 7,334 ± 837 | 0.109 | 0.237 | 0.331 |
| Caudate | 3,425 ± 396 | 3,438 ± 411 | 0.053 | 0.019 | 0.050 |
| Putamen | 4,598 ± 631 | 4,515 ± 617 | 0.258 | 0.559 | 0.016 |
| Pallidum | 1,964 ± 205 | 2,290 ± 328 | 0.010 | 0.000 | 0.000* |
| Hippocampus | 4,004 ± 350 | 3,999 ± 380 | 0.004 | 0.488 | 0.136 |
| Amygdala | 1,669 ± 202 | 1,584 ± 223 | 0.038 | 0.648 | 0.001* |
| Accumbens | 469 ± 87 | 390 ± 75 | 0.069 | 0.564 | 0.000* |
M-W/t-test: Mann-Whitney U nonparametric test for volumes that were not normally distributed in either group and two-sample test for volumes that were normally distributed in both groups, S-W: Shapiro-Wilk test for normality of distribution. All statistical tests were performed on volumes that were averaged across both hemispheres and normalized to the total intracranial volume.
Significant p values that are below the statistical threshold of p < 0.007 (0.05/7).