Fig. 1.
Measures of chronic kidney disease (phosphate and parathyroid hormone (PTH), and intact FGF23 (iFGF23)). a Serum phosphate was not statistically different in male or female mice (p=0.177 and p=0.207, respectively). b PTH was elevated in older, male animals on casein diet as compared to those on the chow diet (diet p=0.019, ES=0.226) but there was no difference in female mice (p=0.541). c iFGF23 in male mice was elevated in aging animals and further elevated in those on casein diet (diet p=0.014, ES=0.265). d iFGF23 in female mice was higher overall as compared to male mice, with older animals on casein diet having the highest levels (diet p<0.0001, ES=0.788; age p<0.0001, ES=0.599; interaction p=0.004, ES=0.309). Group sizes of 6–8. Data plotted as mean and standard deviation with point plots representing individual animal data. Bars not sharing the same letter are statistically different.
