Table 2.
Slope, β, and significance, p, of the regression terms incorporated in the multiple linear regression given by: MWF ~ β0 + βWC × WC + βage × age + βage2 ×age2 + βsex × sex + βethnicity × ethnicity. The results of sex and ethnicity are not shown as they exhibited non-significant associations with MWF in all ROIs. All p-values presented are obtained after FDR correction.
| MWF | ||||||
|---|---|---|---|---|---|---|
| WC | Age | Age2 | ||||
| βWC (× 104) | pWC | βage (× 104) | page | βage2 (× 105) | page2 | |
| WB | −8.28 | 0.005 | −6.23 | 0.000 | −2.30 | 0.003 |
| FL | −9.02 | 0.005 | −7.52 | 0.000 | −2.56 | 0.003 |
| OL | −8.83 | 0.008 | −4.67 | 0.000 | −2.56 | 0.008 |
| PL | −9.08 | 0.005 | −5.30 | 0.000 | −2.34 | 0.003 |
| TL | −9.36 | 0.005 | −7.57 | 0.000 | −2.44 | 0.008 |
| CRB | −5.98 | 0.026 | −3.83 | 0.000 | −1.29 | 0.058 |
| BCC | −8.51 | 0.011 | −6.52 | 0.000 | −2.05 | 0.016 |
| GCC | −8.69 | 0.005 | −8.55 | 0.000 | −1.79 | 0.014 |
| SCC | −8.57 | 0.007 | −5.93 | 0.000 | −2.76 | 0.003 |
| IC | −7.61 | 0.011 | −6.31 | 0.000 | −1.95 | 0.011 |
| CP | −5.89 | 0.023 | −2.45 | 0.000 | −1.10 | 0.089 |
| ACR | −10.90 | 0.005 | −9.10 | 0.000 | −2.23 | 0.011 |
| PCR | −13.66 | 0.002 | −9.65 | 0.000 | −2.96 | 0.003 |
| ATR | −10.35 | 0.005 | −7.67 | 0.000 | −1.78 | 0.023 |
| PTR | −10.16 | 0.005 | −8.41 | 0.000 | −2.40 | 0.006 |
| SFOF | −8.59 | 0.008 | −9.48 | 0.000 | −2.54 | 0.003 |
| IFOF | −9.34 | 0.008 | −8.02 | 0.000 | −2.38 | 0.009 |
| SLF | −12.08 | 0.000 | −7.20 | 0.000 | −2.44 | 0.003 |
| ILF | −9.71 | 0.007 | −6.43 | 0.000 | −2.30 | 0.008 |
| Fm | −10.01 | 0.005 | −6.072 | 0.000 | −2.56 | 0.003 |
| FM | −3.95 | 0.210 | −3.32 | 0.003 | −2.56 | 0.029 |
MWF: myelin water fraction, WC: waist circumference, WB: whole brain, FL: frontal lobes, PL: parietal lobes, TL: temporal lobes, OL: occipital lobes, CRB: cerebellum, BCC: body of corpus callosum, GCC: genu of corpus callosum, SCC: splenium of corpus callosum, IC: internal capsules, CP: cerebral peduncle, ACR: anterior corona radiata, PCR: posterior corona radiata, ATR: anterior thalamic radiation, PTR: posterior thalamic radiation, IFOF: inferior fronto-occipital fasciculus, SFOF: superior fronto-occipital fasciculus, ILF: inferior longitudinal fasciculus, SLF: superior longitudinal fasciculus, Fm: forceps minor, FM: forceps major.