Table 3.

Significance, p-value, of the between-group ANCOVA analyses of the effect of BMI or WC on MWF in all ROIs. All between-group comparisons were controlled for age, age², sex, and ethnicity. All p-values presented are obtained after FDR correction.

	Obese vs. Lean		Overweight vs. Lean		Obese vs. Overweight
	BMI	WC	BMI	WC	BMI	WC
WB	0.033	0.002	0.865	0.165*	0.0156	0.045
FL	0.033	0.002	0.967	0.165*	0.0150	0.040
OL	0.046	0.003	0.936	0.165	0.038	0.528
PL	0.030	0.000	0.927	0.100	0.0156	0.040
TL	0.033	0.002	0.754	0.166*	0.145	0.043
CRB	0.063	0.004	0.608	0.131	0.238	0.726
BCC	0.045	0.002	0.979	0.180*	0.086	0.528
GCC	0.030	0.006	0.795	0.165	0.038	0.400
SCC	0.030	0.002	0.763	0.147	0.015	0.528
IC	0.054	0.011	0.984	0.294	0.034	0.400*
CP	0.126	0.016	0.722	0.180	0.213	0.522
ACR	0.030	0.003	0.706	0.215	0.038	0.528*
PCR	0.003	0.000	0.288	0.012	0.015	0.528
ATR	0.046	0.008	0.538	0.165*	0.102*	0.462
PTR	0.030	0.002	0.712	0.037	0.038	0.528
SFOF	0.037	0.003	0.281	0.215	0.086	0.405
IFOF	0.064	0.007	0.735	0.355	0.039	0.400*
SLF	0.003	0.000	0.312	0.091	0.015	0.401*
ILF	0.050	0.004	0.722	0.309	0.015	0.401*
Fm	0.033	0.002	0.827	0.031	0.038	0.533
FM	0.096	0.236	0.584*	0.674	0.010	0.528

MWF: myelin water fraction, BMI: body mass index, WB: whole brain, FL: frontal lobes, PL: parietal lobes, TL: temporal lobes, OL: occipital lobes, CRB: cerebellum, BCC: body of corpus callosum, GCC: genu of corpus callosum, SCC: splenium of corpus callosum, IC: internal capsules, CP: cerebral peduncle, ACR: anterior corona radiata, PCR: posterior corona radiata, ATR: anterior thalamic radiation, PTR: posterior thalamic radiation, IFOF: inferior fronto-occipital fasciculus, SFOF: superior fronto-occipital fasciculus, ILF: inferior longitudinal fasciculus, SLF: superior longitudinal fasciculus, Fm: forceps minor, FM: forceps major.

^*indicates significance or close to significance before FDR correction (but lost significance after FDR correction).