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View full-text article in PMC

. Author manuscript; available in PMC: 2021 Jul 1.

Published in final edited form as: Front Phys. 2021 Jan 27;8:625424.

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FIGURE 1 | — (A) A small time-gated immunoassay platform integrating a time-gated optical detector and microplate-based immunoassay using Mn:AgZnInS/ZnS NC probes as signal transducers. (B) Principle illustration of the optical unit. (C) The immunoassay format performed in microwells of microplates: after antigens are switched between antibody-coated magnetic microbeads and antibody-conjugated NC probes, the NC probes are released from the immuno-switch-complexes into supernatants for time-gated signal measurement. (D) The timing sequence for time-gated measurement on the excitation laser and the PMT.