Figure 7. TXNIP levels are increased in older human cartilage sections.
TXNIP levels in normal younger and normal older human knee cartilage tissue sections were evaluated by immunohistochemistry. Tissue sections were counterstained with hematoxylin. Human cartilage sections (n=3 independent samples) were macroscopically graded as described in ‘Experimental Procedures’. Younger tissues were from adults <50 years old (mean age, 43.0±6.2 yrs.), and older tissues were from adults >65 years old (mean age, 73.3±4.6 yrs.). Scale bar, 100μM. Data are presented as percentage TXNIP stained cells for young and old cartilage sections. Unpaired t-test was used to test for statistical differences between groups.
