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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Bone. 2021 Feb 19;146:115889. doi: 10.1016/j.bone.2021.115889

Figure 4.

Figure 4.

Mechanical properties of right and left tibiae; standard-CON (n=10), standard-RAL (n=12), thermoneutral-CON (n=11), thermoneutral-RAL (n=12). A) Average force-displacement plot for standard temperature, showing stronger loaded bones (mean +/− SEM). B) The strength disparity continued at the thermoneutral temperature as quantified by C) the ultimate force. D) Average stress-strain plots for mice housed at standard temperature show how tissue-level properties increase with loading and RAL, E) with similar results at thermoneutral temperature. F) Bone toughness increases with loading and RAL treatment. **** p<0.0001, ** p=0.0092, * p≤0.05.