Table 1.

Trabecular properties of right (non-loaded) and left (loaded) tibiae (n=20 per group). RM 3-way ANOVA test with temperature (temp), loading (load), and treatment (treat) main effects.

	Standard				Thermoneutral				P-value
	Non-loaded		Loaded		Non-loaded		Loaded		Temperature	Loading	Treatment	Temperature * Loading	Temperature * Treatment	Loading * Treatment	Temperature * Loading * Treatment
	Control	RAL	Control	RAL	Control	RAL	Control	RAL
BV/TV (%)	12 ± 2.1	16.2 ± 2.3	16.4 ± 3.4	20.3 ± 3.2	12.3 ± 2	15.5 ± 2.1	17.7 ± 1.9	20.8 ± 2.6	0.5026	<0.0001	<0.0001	0.0074	0.4264	0.6676	0.9690
Tb.Th (μm)	6.14 ± 0.21	6.73 ± 0.26	7.68 ± 0.71	7.91 ± 0.42	6.14 ± 0.19	6.61 ± 0.2	7.39 ± 0.31	7.82 ± 0.3	0.0297	<0.0001	<0.0001	0.2884	0.7485	0.0937	0.1595
Tb.Sp (μm)	23.66 ± 1.98	22.68 ± 1.51	23.1 ± 2.85	21.55 ± 1.65	23.58 ± 1.67	22.23 ± 1.68	21.52 ± 1.7	21.27 ± 1.93	0.1352	<0.0001	0.0107	0.0465	0.5541	0.4041	0.0129
Tb.N (1/μm)	0.02 ± 0	0.02 ± 0	0.02 ± 0	0.03 ± 0	0.02 ± 0	0.02 ± 0	0.02 ± 0	0.03 ± 0	0.2550	<0.0001	<0.0001	0.0003	0.4093	0.3230	0.3968
TMD (g/cm3)	0.74 ± 0.01	0.76 ± 0.02	0.78 ± 0.03	0.78 ± 0.02	0.75 ± 0.02	0.76 ± 0.02	0.76 ± 0.02	0.78 ± 0.02	0.8218	<0.0001	<0.0001	0.0615	0.8950	0.1820	0.0083