Figure 5.

HCN2 phosphorylation levels in epilepsy vs naïve conditions in rat. Shown are the phosphorylation levels of ten HCN2 phosphosites (where phosphorylation was detected in ≥ 50% of rat samples) between chronically epileptic rats (6–9 weeks post-SE) versus age-matched naïve animals. The limits of each box show the 25^th and 75^th percentiles of the data values; the median is depicted as the line within the box; and the whiskers show the 95^th and 5^th percentiles. No significant phosphorylation changes were observed between chronically epileptic and naïve animals.