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. 2021 Mar 30;12:1968. doi: 10.1038/s41467-021-22138-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Layout of multimodal optogenetic stimulator and thermography device. b Electrical diagram of analog front end, indicating location of resistors, negative temperature coefficient (NTC) sensor, amplifier (Amp), reference voltage (V_ref), and output voltage (V_out). c Calibration curve of ADC values and temperatures with 1.8 mK resolution. d Simplified electronic diagram (top left) and side view schematic of multimodal optogenetic stimulator and thermography device (top right) with voltage measurement of capacitor bank (black trace), power measurement of μC (orange trace), and voltage measurement of IR LED (red trace) (bottom). Green highlighted area indicates sampling of the ADC and writing of EEPROM and violet highlighted area indicates sending of 8-bit fragment. e Rendering of experimental arena showing data uplink and power delivery to animal with implanted device. f Spatial distribution of uplink stability.