TABLE 2.
Control | Untreated MI | Lipoic acid | Zinc | Clopidogrel | |
(25) | (16) | (24) | (24) | (25) | |
ST-segment (mm) | 0.63 ± 0.11 | 1.75 ± 0.14a | 0.90 ± 0.13b | 0.90 ± 0.18b | 1.07 ± 0.07ab |
HR (bpm) | 406.75 ± 18.79 | 419.61 ± 16.10 | 426.00 ± 12.53 | 439.93 ± 17.63 | 461.60 ± 15.35a |
QTo (msec) | 81.25 ± 2.21 | 116.19 ± 4.05a | 125.33 ± 3.63a | 102.67 ± 3.84ab | 86.67 ± 2.52b |
QTc (msec) | 210.81 ± 8.50 | 275.33 ± 17.02a | 335.33 ± 9.79ab | 277.93 ± 13.25a | 238.33 ± 6.63ab |
QRS duration (msec) | 23.75 ± 2.02 | 28.10 ± 2.03 | 37.33 ± 1.82ab | 48.00 ± 1.60ab | 33.33 ± 2.52a |
QRS voltage (μvolt) | 478.13 ± 31.61 | 473.81 ± 26.42 | 471.33 ± 53.21 | 255 ± 38.16ab | 501.67 ± 32.04 |
Values are represented as mean ± SEM. The number of observations is given in parentheses. MI, myocardial infarction; HR, heart rate; QTo, QT interval observed; QTc, QT interval corrected. aSignificance of differences from control group calculated by Student’s t-test for unpaired data at p < 0.05. bSignificance of differences from MI group calculated by Student’s t-test for unpaired data at p < 0.05.